Hormonal fluctuations play a significant role in mood changes throughout a woman’s lifespan. In this episode, Dr. Rae Littlewood is joined by special guest Dr. Liza Mermelstein to share information about the relationship between mood and estrogen, provide guidance in differentiating between depression, PMS, and PMDD (prementrual dysphoric disorder), and review self-care and treatment options. We also touch on the relationship between estrogen fluctuation during perimenopause and increased risk for depression during this transition. Stay tuned for part 2 to learn more about hormones and mood in relation to trying to conceive and prenatal and postpartum adjustment.